A Novel Mitragynine Analog with Low-Efficacy Mu Opioid Receptor Agonism Displays Antinociception with Attenuated Adverse Effects | Journal of Medicinal Chemistry
Kappa Opioid Receptor Structure Revealed, A Potential Milestone in Medication Development | National Institute on Drug Abuse (NIDA)
Kratom (Mitragyna speciosa) drug profile | www.emcdda.europa.eu
Molecules | Free Full-Text | Biased Opioid Ligands
Opioid-based plant might not be best solution for those seeking to curb habitual alcohol use - Purdue University News
Scientists Just Solved a Major Piece of the Opioid Puzzle | WIRED
Targeting the Kappa Opioid Receptor to Reduce Drug Use and Relapse | National Institute on Drug Abuse (NIDA)
Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions | Scientific Reports
Opioid receptors: drivers to addiction? | Nature Reviews Neuroscience
The medicinal chemistry and neuropharmacology of kratom: A preliminary discussion of a promising medicinal plant and analysis of its potential for abuse - ScienceDirect
An updated assessment of the translational promise of G-protein-biased kappa opioid receptor agonists to treat pain and other indications without debilitating adverse effects - ScienceDirect
Pharmacological characterization of kratom derivatives at the µ, δ, and... | Download Scientific Diagram
Frontiers | Kratom Use Within the Context of the Evolving Opioid Crisis and the COVID-19 Pandemic in the United States
κ-opioid receptor - Wikipedia
Mitragynine - Wikipedia
Pharmaceutics | Free Full-Text | Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants
Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators | Journal of the American Chemical Society
Kratom - Proteopedia, life in 3D
The science behind kratom's strange leaves
Neurobiology of Kratom and its main alkaloid mitragynine
Majumdar Lab - Research Projects
Influence of G protein-biased agonists of μ-opioid receptor on addiction-related behaviors | SpringerLink
Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom | ACS Chemical Neuroscience
The effects of kratom on restraint–stress-induced analgesia and its mechanisms of action - ScienceDirect
G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder - Gutridge - 2020 - British Journal of Pharmacology - Wiley Online Library
Medicines | Free Full-Text | Mitragyna speciosa: Clinical, Toxicological Aspects and Analysis in Biological and Non-Biological Samples
Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators | Journal of the American Chemical Society
Evaluating kratom alkaloids using PHASE | PLOS ONE
Central nervous system receptor binding data for mitragynine.... | Download Table
